We manufacture high quality biochemicals, assay kits, antibodies, and recombinant proteins and offer contract services for Bioanalysis and Assay Development, Medicinal Chemistry and Structure-Based Drug Design, Analytical Chemistry, and Chemical Synthesis.
Our mission is to help make research possible. That starts by employing a talented and highly qualified group of experts to develop the tools to support research scientists across academic, biotechnology, and pharmaceutical institutions. Visit us at www.caymanchem.com.
Sixty staff chemists synthesize, purify, and characterize the small molecules and biochemicals you need to take your research further, including drug-like heterocycles, complex biolipids and fatty acids, inhibitors, activators, and modulators. Search by CAS number, common name, synonyms, InCHI Code, InCHI key, SMILES, or molecular weight, or explore by research area to find what you need. Bulk pricing, custom aliquots, and exact weights are available upon your request. Not finding what you're looking for? Contact our custom organic service staff for affordable pricing on the synthesis of your custom molecule.
With hundreds of assay kits in a variety of formats to choose from, Cayman offers complete solutions to quickly monitor biomarkers, assess cellular health, and measure enzyme activity/inhibition. Each of our assay kits undergoes rigorous quality testing to certify high precision and accuracy to deliver the sensitivity and specificity needed to detect biologically significant analyte levels.
For everywhere your research leads, we provide a catalog of hundreds of recombinant proteins expressed and purified from bacterial, insect, and mammalian expression systems. We clone, express, and purify proteins and active enzymes at our facility in Ann Arbor, Michigan. Your research requires consistency, so our scientific staff thoroughly tests activity and quality to ensure low variability from lot to lot. Bulk proteins are available upon your request.
We offer primary and secondary antibodies for diverse applications, including western blot, flow cytometry, immunohistochemistry, and immunofluorescence. Our antibodies are validated on biological tissues and cell lysates to ensure they will be reliable tools for your research. We provide target receptors, proteins, enzymes, and post-translational modifications for eicosanoid, neuroscience, immunology, inflammation, cancer, and epigenetic research. Secondary antibodies are available with HRP, AP, fluorescein, rhodamine, phycoerythrin, APC, europium, biotin, Texas red, and more. Custom production, purification, and conjugation services and bulk antibody orders are available upon your request.
Bioanalysis and Assay Development
Our scientists perform sample analysis, compound screening, and assay development. Choose from our catalog of well-characterized Cayman assays or other qualified commercially available assays. Our experts can also develop and qualify an assay that suits your specific requirements. Our team has decades of experience developing plate-based, mass spectrometry-based, cell-based, and flow cytometry assays. We consult with you continuously throughout the project—from experimental design to data analysis and reporting—ensuring we meet your objectives.
Medicinal Chemistry and Structure-Based Drug Design
Our Medicinal Chemistry & Structure-Based Drug Design services offer a fully integrated, multidisciplinary approach to developing a wide range of therapeutics. Our scientists have the expertise and technology to bring your drug discovery program through pre-clinical stages of development. Whether it’s lead generation or optimization, route and methods development, screening, or scale-up, Cayman’s experienced medicinal and organic chemists, structural biologists, and biochemists possess the competencies to accelerate your pre-clinical drug discovery programs.
Our scientists perform routine quality control testing on thousands of compounds each year, giving Cayman unparalleled expertise in the development and validation of methods to analyze, quantify, and purify small molecules. Employing multiple chemical testing methods customized to each project’s unique requirements, we perform qualitative and quantitative analysis, purification, and characterization of chemical entities such as bioactive lipids, natural products, synthetic compounds, cosmetics, pharmaceuticals, and drugs of abuse in organic and biological matrices.
Our team of synthetic organic and medicinal chemists brings decades of industry experience to perform complex, multi-step organic syntheses. Supported by our Medicinal Chemistry & Structure-Based Drug Design and GMP & Process Development Services, our team of highly skilled organic chemists includes broad synthetic proficiencies beyond our core expertise in lipid, bioconjugate, and stable isotopic labeling chemistry.