Edit |   |
---|---|
Antigenic Specificity | Peroxisomal Biogenesis Factor 5 (PEX5) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PEX5 antibody is a Rabbit polyclonal antibody against PEX5. The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. |
Immunogen | Recombinant protein of human PEX5. |
Other Names | PEX5, PBD2A, PBD2B, Peroxisome receptor 1, PTS1 receptor, PTS1-BP, PTS1R, PXR1, Peroxin-5, peroxisomal biogenesis factor 5, FLJ50634, FLJ50721, FLJ51948, OTTHUMP00000238192, OTTHUMP00000238193, OTTHUMP00000238194, OTTHUMP00000238195, OTTHUMP00000238353, OTTHUMP00000238354, OTTHUMP00000238356, Peroxisomal targeting signal 1 receptor, Peroxisomal C-terminal targeting signal import receptor, PEX5, PEX5, PEX5 , PEX5 , PBD2A, PBD2A, PBD2A , PBD2A , PBD2B, PBD2B, PBD2B , PBD2B , Peroxisome receptor 1, Peroxisome receptor 1, Peroxisome receptor 1 , Peroxisome receptor 1 , PTS1 receptor, PTS1 receptor, PTS1 receptor , PTS1 receptor , PTS1-BP, PTS1-BP, PTS1-BP , PTS1-BP , PTS1R, PTS1R, PTS1R , PTS1R , PXR1, PXR1, PXR1 , PXR1 , Peroxin-5, Peroxin-5, Peroxin-5 , Peroxin-5 , peroxisomal biogenesis factor 5, peroxisomal biogenesis factor 5, peroxisomal biogenesis factor 5 , peroxisomal biogenesis factor 5 , FLJ50634, FLJ50634, FLJ50634 , FLJ50634 , FLJ50721, FLJ50721, FLJ50721 , FLJ5072 |
Gene, Accession # | PEX5, Gene ID: 5830, UniProt: P50542 |
Catalog # | abx004428 |
Price | please inquire |
Order / More Info | Peroxisomal Biogenesis Factor 5 (PEX5) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950