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Antigenic Specificity | 2'-5'-Oligoadenylate Synthetase 1 (OAS1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | OAS1 antibody is a Rabbit polyclonal antibody against OAS1. This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
Immunogen | Recombinant protein of human OAS1. |
Other Names | OAS1, 2'-5'-Oligoadenylate Synthetase 1, 2-5-Oligoadenylate Synthetase 1, 2-5-Oligoadenylate Synthetase 1, 40/46kDa, (2-5)Oligo(A) Synthase 1, 2-5A Synthase 1, E18/E16, OIAS, 2,5-Oligoadenylate Synthetase 1 (40-46 KD), 2-5-Oligoisoadenylate Synthetase 1, 2-5-Oligoadenylate Synthase 1, 2-5-Oligoadenylate Synthase 1, E16 (2-5) Oligo A Synthetase, 2,5-Oligo A Synthetase 1, 2-5A Synthetase 1, P46/P42 OAS, EC 2.7.7.84, IFI-4, OIASI, OAS1, OAS1, OAS1 , OAS1 , 2'-5'-Oligoadenylate Synthetase 1, 2'-5'-Oligoadenylate Synthetase 1, 2'-5'-Oligoadenylate Synthetase 1 , 2'-5'-Oligoadenylate Synthetase 1 , 2-5-Oligoadenylate Synthetase 1, 2-5-Oligoadenylate Synthetase 1, 2-5-Oligoadenylate Synthetase 1 , 2-5-Oligoadenylate Synthetase 1 , 2-5-Oligoadenylate Synthetase 1, 40/46kDa, 2-5-Oligoadenylate Synthetase 1, 40/46kDa, 2-5-Oligoadenylate Synthetase 1, 40/46kDa , 2-5-Oligoadenylate Synthetase 1, 40/46kDa , (2-5)Oligo(A) Synthase 1, (2-5)Oligo(A) Synthase 1, (2-5)Oligo(A) Synthase 1 , (2-5)Oli |
Gene, Accession # | OAS1, Gene ID: 4938, UniProt: P00973 |
Catalog # | abx001970 |
Price | please inquire |
Order / More Info | 2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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