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Antigenic Specificity | F-Box/WD Repeat-Containing Protein 1A (BTRC) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BTRC antibody is a Rabbit polyclonal antibody against BTRC. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. |
Immunogen | Recombinant protein of human BTRC. |
Other Names | BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, MGC4643, bTrCP, bTrCP1, betaTrCP, BTRC, F-box/WD repeat-containing protein 1A, E3RSIkappaB, Epididymis tissue protein Li 2a, F-box and WD repeats protein beta-TrCP, pIkappaBalpha-E3 receptor subunit, pIkappaBalpha-E3 receptor subuni, BETA-TRCP, BETA-TRCP, BETA-TRCP , BETA-TRCP , FBW1A, FBW1A, FBW1A , FBW1A , FBXW1, FBXW1, FBXW1 , FBXW1 , FBXW1A, FBXW1A, FBXW1A , FBXW1A , FWD1, FWD1, FWD1 , FWD1 , MGC4643, MGC4643, MGC4643 , MGC4643 , bTrCP, bTrCP, bTrCP , bTrCP , bTrCP1, bTrCP1, bTrCP1 , bTrCP1 , betaTrCP, betaTrCP, betaTrCP , betaTrCP , BTRC, BTRC, BTRC , BTRC , F-box/WD repeat-containing protein 1A, F-box/WD repeat-containing protein 1A, F-box/WD repeat-containing protein 1A , F-box/WD repeat-containing protein 1A , E3RSIkappaB, E3RSIkappaB, E3RSIkappaB , E3RSIkappaB , Epididymis tissue protein Li 2a, Epididymis tissue protein Li 2a, Epididymis tissue protein Li 2a , Epididymis tissue protein Li 2a , F-box and WD repeats protein bet |
Gene, Accession # | BTRC, Gene ID: 8945, UniProt: Q9Y297 |
Catalog # | abx001393 |
Price | please inquire |
Order / More Info | F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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