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Antigenic Specificity | HLA Class II Histocompatibility Antigen, DP Beta 1 Chain (HLA-DPB1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-DPB1 antibody is a Rabbit polyclonal antibody against HLA-DPB1. HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
Immunogen | Recombinant protein of human HLA-DPB1. |
Other Names | DPB1, HLA-DP, HLA-DPB, HLA-DP1B, Hla Class Ii Histocompatibility Antigen, Dp(W4) Beta Chain, Mhc Class Ii Antigen Dpb1, Hla-Dpb1, DP beta 1 chain, DP (W4) beta chain, DPB1, DPB1, DPB1 , DPB1 , HLA-DP, HLA-DP, HLA-DP , HLA-DP , HLA-DPB, HLA-DPB, HLA-DPB , HLA-DPB , HLA-DP1B, HLA-DP1B, HLA-DP1B , HLA-DP1B , Hla Class Ii Histocompatibility Antigen, Hla Class Ii Histocompatibility Antigen, Hla Class Ii Histocompatibility Antigen , Hla Class Ii Histocompatibility Antigen , Dp(W4) Beta Chain, Dp(W4) Beta Chain, Dp(W4) Beta Chain , Dp(W4) Beta Chain , Mhc Class Ii Antigen Dpb1, Mhc Class Ii Antigen Dpb1, Mhc Class Ii Antigen Dpb1 , Mhc Class Ii Antigen Dpb1 , Hla-Dpb1, Hla-Dpb1, Hla-Dpb1 , Hla-Dpb1 , DP beta 1 chain, DP beta 1 chain, DP beta 1 chain , DP beta 1 chain , DP (W4) beta chain, DP (W4) beta chain, DP (W4) beta chain , DP (W4) beta chain |
Gene, Accession # | HLA-DPB1, Gene ID: 3115, UniProt: P04440 |
Catalog # | abx001225 |
Price | please inquire |
Order / More Info | HLA Class II Histocompatibility Antigen, DP Beta 1 Chain (HLA-DPB1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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