Hexokinase-4 (GCK) Antibody from ABBEXA LTD

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Antigenic SpecificityHexokinase-4 (GCK)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionHexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2) ; mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
ImmunogenKLH-conjugated synthetic peptide between 403-433 amino acids from the C-terminal region of human GCK.
Other NamesGCK, FGQTL3, Glucokinase, HK IV, HKIV, Hexokinase d, liver isozymes, Hexokinase-4, Hexokinase-D, HXKP, GLK, Glucokinase (hexokinase 4), Hexokinase type IV, HHF3, HK4, LGLK, MODY2, GK, GCK, GCK, GCK , GCK , FGQTL3, FGQTL3, FGQTL3 , FGQTL3 , Glucokinase, Glucokinase, Glucokinase , Glucokinase , HK IV, HK IV, HK IV , HK IV , HKIV, HKIV, HKIV , HKIV , Hexokinase d, Hexokinase d, Hexokinase d , Hexokinase d , liver isozymes, liver isozymes, liver isozymes , liver isozymes , Hexokinase-4, Hexokinase-4, Hexokinase-4 , Hexokinase-4 , Hexokinase-D, Hexokinase-D, Hexokinase-D , Hexokinase-D , HXKP, HXKP, HXKP , HXKP , GLK, GLK, GLK , GLK , Glucokinase (hexokinase 4), Glucokinase (hexokinase 4), Glucokinase (hexokinase 4) , Glucokinase (hexokinase 4) , Hexokinase type IV, Hexokinase type IV, Hexokinase type IV , Hexokinase type IV , HHF3, HHF3, HHF3 , HHF3 , HK4, HK4, HK4 , HK4 , LGLK, LGLK, LGLK , LGLK , MODY2, MODY2, MODY2 , MODY2 , GK, GK, GK , GK
Gene, Accession #NCBI: NP_000153.1, NP_277042.1, NP_277043.1, UniProt: P35557
Catalog #abx033753
Priceplease inquire
Order / More InfoHexokinase-4 (GCK) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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