Abelson Tyrosine-Protein Kinase 2 (ABL2) Antibody from ABBEXA LTD

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Antigenic SpecificityAbelson Tyrosine-Protein Kinase 2 (ABL2)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB, IF/ICC
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DescriptionABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases.ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half.The human c-Abl and ABL2 genes are expressed ubiquitously.ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization.c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML).The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
ImmunogenPurified recombinant fragment of ABL2 expressed in E. coli.
Other NamesABL2, ABLL, ARG, Abelson tyrosine-protein kinase 2, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine-protein kinase ARG, FLJ22224, FLJ31718, FLJ41441, ABL2, ABL2, ABL2 , ABL2 , ABLL, ABLL, ABLL , ABLL , ARG, ARG, ARG , ARG , Abelson tyrosine-protein kinase 2, Abelson tyrosine-protein kinase 2, Abelson tyrosine-protein kinase 2 , Abelson tyrosine-protein kinase 2 , Abelson murine leukemia viral oncogene homolog 2, Abelson murine leukemia viral oncogene homolog 2, Abelson murine leukemia viral oncogene homolog 2 , Abelson murine leukemia viral oncogene homolog 2 , Abelson-related gene protein, Abelson-related gene protein, Abelson-related gene protein , Abelson-related gene protein , Tyrosine-protein kinase ARG, Tyrosine-protein kinase ARG, Tyrosine-protein kinase ARG , Tyrosine-protein kinase ARG , FLJ22224, FLJ22224, FLJ22224 , FLJ22224 , FLJ31718, FLJ31718, FLJ31718 , FLJ31718 , FLJ41441, FLJ41441, FLJ41441 , FLJ41441
Gene, Accession #ABL2, Gene ID: 27, UniProt: P42684
Catalog #abx015718
Priceplease inquire
Order / More InfoAbelson Tyrosine-Protein Kinase 2 (ABL2) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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