Mothers Against Decapentaplegic Homolog 2 (SMAD2) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Mothers Against Decapentaplegic Homolog 2 (SMAD2) antibody, protein, ELISA kits.
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| Antigenic Specificity | Mothers Against Decapentaplegic Homolog 2 (SMAD2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IF/ICC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein belongs to the SMAD, a family of proteins similar to the proteins of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. |
| Immunogen | KLH-conjugated synthetic peptide between 97-125 amino acids from human SMAD2. |
| Other Names | JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, MGC22139, MGC34440, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against, Mothers against decapentaplegic homolog 2, Smad 2, MAD homolog 2, SMAD family member 2, Smad2, SMAD3, MADH3, Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, hSMAD3, V18, JV18, JV18, JV18 , JV18 , MADH2, MADH2, MADH2 , MADH2 , MADR2, MADR2, MADR2 , MADR2 , JV18-1, JV18-1, JV18-1 , JV18-1 , hMAD-2, hMAD-2, hMAD-2 , hMAD-2 , hSMAD2, hSMAD2, hSMAD2 , hSMAD2 , MGC22139, MGC22139, MGC22139 , MGC22139 , MGC34440, MGC34440, MGC34440 , MGC34440 , Mad-related protein 2, Mad-related protein 2, Mad-related protein 2 , Mad-related protein 2 , Mothers against DPP homolog 2, Mothers against DPP homolog 2, Mothers against DPP homolog 2 , Mothers against DPP homolog 2 , Mothers against, Mothers against, Mothers against , Mothers against , Mothers against decapentapleg |
| Gene, Accession # | UniProt: Q15796 |
| Catalog # | abx033353 |
| Price | please inquire |
| Order / More Info | Mothers Against Decapentaplegic Homolog 2 (SMAD2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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