Platelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody from ABBEXA LTD

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Antigenic SpecificityPlatelet Derived Growth Factor Receptor Beta (PDGFRB)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionPlatelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFR beta or CD140B. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFR alpha) and PDGF receptor beta (PDGFR beta). These growth factors are mitogens for cells of mesenchymal origin. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
ImmunogenPurified recombinant fragment of human PDGFR beta expressed in E. Coli.
Other NamesCD140b, PDGF-R-beta, PDGFR, PDGFR-beta, PGFRB, kinase PDGFR-beta, JTK12, PDGFR1, PDGFRB, PDGFR beta, CD140b, CD140b, CD140b , CD140b , PDGF-R-beta, PDGF-R-beta, PDGF-R-beta , PDGF-R-beta , PDGFR, PDGFR, PDGFR , PDGFR , PDGFR-beta, PDGFR-beta, PDGFR-beta , PDGFR-beta , PGFRB, PGFRB, PGFRB , PGFRB , kinase PDGFR-beta, kinase PDGFR-beta, kinase PDGFR-beta , kinase PDGFR-beta , JTK12, JTK12, JTK12 , JTK12 , PDGFR1, PDGFR1, PDGFR1 , PDGFR1 , PDGFRB, PDGFRB, PDGFRB , PDGFRB , PDGFR beta, PDGFR beta, PDGFR beta , PDGFR beta
Gene, Accession #Gene ID: 5159, UniProt: P09619
Catalog #abx011361
Priceplease inquire
Order / More InfoPlatelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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