STIP1 Homology And U-Box Containing Protein 1 (STUB1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-STIP1 Homology And U-Box Containing Protein 1 (STUB1) antibody, protein, ELISA kits.
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| Antigenic Specificity | STIP1 Homology And U-Box Containing Protein 1 (STUB1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | STUB1 antibody is a Rabbit polyclonal antibody against STUB1. The carboxy terminus of Hsc70-interacting protein (CHIP, STUB1) is a co-chaperone protein and functional E3 ubiquitin ligase that links the polypeptide binding activity of Hsp70 to the ubiquitin proteasome systemCytoplasmic CHIP protein contains three 34-amino acid TPR (tetRatricopeptide repeat) domains at its amino terminus and a carboxy-terminal U-box domainCHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain, while E3 ubiquitin ligase activity is confined to the U-box domainThe binding of CHIP to Hsp70 can stall the folding of Hsp70 client proteins and concomitantly facilitate the U-box dependent ubiquitination of Hsp70-bound substRatesCHIP appears to play a central role in cell stress protection and is responsible for the degradation of disease-related proteins that include cystic fibrosis transmembrane conductance regulator, p53, huntingtin and Ataxin-3, Tau protein, and ?-synuclein. |
| Immunogen | Recombinant protein of human STUB1. |
| Other Names | E3 ubiquitin-protein ligase CHIP, Antigen NY-CO-7, STUB1, CHIP, CLL-associated antigen KW-8, Carboxy terminus of Hsp70-interacting protein, STIP1 homology and U box-containing protein 1, HSPABP2, NY-CO-7, SDCCAG7, UBOX1, E3 ubiquitin-protein ligase CHIP, E3 ubiquitin-protein ligase CHIP, E3 ubiquitin-protein ligase CHIP , E3 ubiquitin-protein ligase CHIP , Antigen NY-CO-7, Antigen NY-CO-7, Antigen NY-CO-7 , Antigen NY-CO-7 , STUB1, STUB1, STUB1 , STUB1 , CHIP, CHIP, CHIP , CHIP , CLL-associated antigen KW-8, CLL-associated antigen KW-8, CLL-associated antigen KW-8 , CLL-associated antigen KW-8 , Carboxy terminus of Hsp70-interacting protein, Carboxy terminus of Hsp70-interacting protein, Carboxy terminus of Hsp70-interacting protein , Carboxy terminus of Hsp70-interacting protein , STIP1 homology and U box-containing protein 1, STIP1 homology and U box-containing protein 1, STIP1 homology and U box-containing protein 1 , STIP1 homology and U box-containing protein 1 , HSPABP2, |
| Gene, Accession # | STUB1, Gene ID: 10273, UniProt: Q9UNE7 |
| Catalog # | abx117049 |
| Price | please inquire |
| Order / More Info | STIP1 Homology And U-Box Containing Protein 1 (STUB1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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