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Antigenic Specificity | Ring Finger Protein 19A, RBR E3 Ubiquitin Protein Ligase (RNF19A) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported. |
Immunogen | KLH-conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A. |
Other Names | RNF19A, DORFIN, Double ring-finger protein, RING finger protein 19 isoform, RNF19, Ring finger protein 19, p38, p38 protein, RING finger protein 19A, E3 ubiquitin-protein ligase RNF19A, RNF19A, RNF19A, RNF19A , RNF19A , DORFIN, DORFIN, DORFIN , DORFIN , Double ring-finger protein, Double ring-finger protein, Double ring-finger protein , Double ring-finger protein , RING finger protein 19 isoform, RING finger protein 19 isoform, RING finger protein 19 isoform , RING finger protein 19 isoform , RNF19, RNF19, RNF19 , RNF19 , Ring finger protein 19, Ring finger protein 19, Ring finger protein 19 , Ring finger protein 19 , p38, p38, p38 , p38 , p38 protein, p38 protein, p38 protein , p38 protein , RING finger protein 19A, RING finger protein 19A, RING finger protein 19A , RING finger protein 19A , E3 ubiquitin-protein ligase RNF19A, E3 ubiquitin-protein ligase RNF19A, E3 ubiquitin-protein ligase RNF19A , E3 ubiquitin-protein ligase RNF19A |
Gene, Accession # | RNF19A, UniProt: Q9NV58 |
Catalog # | abx027899 |
Price | please inquire |
Order / More Info | Ring Finger Protein 19A, RBR E3 Ubiquitin Protein Ligase (RNF19A) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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