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Antigenic Specificity | 26S Proteasome Regulatory Subunit 6A (PSMC3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µg, |
Concentration | 1 mg/ml. |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal against the 26S Proteasome Regulatory Subunit 6A (PSMC3) protein. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. |
Immunogen | A peptide corresponding to middle region of human PSMC3 protein. |
Other Names | PSMC3, Proteasome 26S Subunit, ATPase 3, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3, 26S Proteasome AAA-ATPase Subunit RPT5, 26S Proteasome Regulatory Subunit 6A, Proteasome Subunit P50, Tat-Binding Protein 1, TBP1, Human Immunodeficiency Virus Tat Transactivator Binding Protein-1, 26S Protease Regulatory Subunit 6A, Testicular Secretory Protein Li 42, Proteasome 26S Subunit ATPase 3, TBP-1, PSMC3, PSMC3, PSMC3 , PSMC3 , Proteasome 26S Subunit, ATPase 3, Proteasome 26S Subunit, ATPase 3, Proteasome 26S Subunit, ATPase 3 , Proteasome 26S Subunit, ATPase 3 , Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3, Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 , Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 , 26S Proteasome AAA-ATPase Subunit RPT5, 26S Proteasome AAA-ATPase Subunit RPT5, 26S Proteasome AAA-ATPase Subunit RPT5 , 26S Proteasome AAA-ATPase Subunit RPT5 , 26S Proteasome Regulatory Subunit |
Gene, Accession # | PSMC3, Gene ID: 5702, NCBI: NM_002804, UniProt: P17980 |
Catalog # | abx037813 |
Price | please inquire |
Order / More Info | 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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