p16-INK4A (pS140) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-p16-INK4A (pS140) antibody, protein, ELISA kits.
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| Antigenic Specificity | p16-INK4A (pS140) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | p16-INK4A functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. This protein acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. The gene for this protein is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S140 of human p16-INK4A. |
| Other Names | CD2A1, CDK4I, CDKN2, CDKN2A, CDN2, Cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor 2A, MTS1, Multiple tumor suppressor 1, p14ARF, p16 (INK4a), p16-INK4, P16INK4A, P16-INK4A, CD2A1, CD2A1, CD2A1 , CD2A1 , CDK4I, CDK4I, CDK4I , CDK4I , CDKN2, CDKN2, CDKN2 , CDKN2 , CDKN2A, CDKN2A, CDKN2A , CDKN2A , CDN2, CDN2, CDN2 , CDN2 , Cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase 4 inhibitor A , Cyclin-dependent kinase 4 inhibitor A , cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A , cyclin-dependent kinase inhibitor 2A , MTS1, MTS1, MTS1 , MTS1 , Multiple tumor suppressor 1, Multiple tumor suppressor 1, Multiple tumor suppressor 1 , Multiple tumor suppressor 1 , p14ARF, p14ARF, p14ARF , p14ARF , p16 (INK4a), p16 (INK4a), p16 (INK4a) , p16 (INK4a) , p16-INK4, p16-INK4, p16-INK4 , p16-INK4 , P16INK4A, P16INK4A, P16INK4A , P16INK4A , P16-INK4A, |
| Gene, Accession # | NCBI: NP_000068.1, NP_001182061.1, NP_478104.2, UniProt: P42771 |
| Catalog # | abx031883 |
| Price | please inquire |
| Order / More Info | p16-INK4A (pS140) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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