Hypoxia Up-Regulated 1 (HYOU1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Hypoxia Up-Regulated 1 (HYOU1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HYOU1 belongs to the heat shock protein 70 family. The protein is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. |
| Immunogen | KLH-conjugated synthetic peptide between 274-303 amino acids from the Central region of human HYOU1. |
| Other Names | 150 kDa oxygen-regulated protein, ORP-150, 170 kDa glucose-regulated protein, GRP-170, HYOU1, GRP170, ORP150, HSP12A, Glucose-regulated protein 170, Hypoxia up-regulated 1, Hypoxia up-regulated protein 1, 150 kDa oxygen-regulated protein, 150 kDa oxygen-regulated protein, 150 kDa oxygen-regulated protein , 150 kDa oxygen-regulated protein , ORP-150, ORP-150, ORP-150 , ORP-150 , 170 kDa glucose-regulated protein, 170 kDa glucose-regulated protein, 170 kDa glucose-regulated protein , 170 kDa glucose-regulated protein , GRP-170, GRP-170, GRP-170 , GRP-170 , HYOU1, HYOU1, HYOU1 , HYOU1 , GRP170, GRP170, GRP170 , GRP170 , ORP150, ORP150, ORP150 , ORP150 , HSP12A, HSP12A, HSP12A , HSP12A , Glucose-regulated protein 170, Glucose-regulated protein 170, Glucose-regulated protein 170 , Glucose-regulated protein 170 , Hypoxia up-regulated 1, Hypoxia up-regulated 1, Hypoxia up-regulated 1 , Hypoxia up-regulated 1 , Hypoxia up-regulated protein 1, Hypoxia up-regulated protein 1, Hypoxia |
| Gene, Accession # | NCBI: NP_001124463.1, NP_006380.1, UniProt: Q9Y4L1 |
| Catalog # | abx033323 |
| Price | please inquire |
| Order / More Info | Hypoxia Up-Regulated 1 (HYOU1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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