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Antigenic Specificity | Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. |
Immunogen | KLH-conjugated synthetic peptide between 214-242 amino acids from the Central region of human TNFRSF25. |
Other Names | TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, Protein WSL, Protein WSL-1, TRAMP, TR3, LARD, WSL-1, WSL-LR, Translocating Chain-Association Membrane Protein, TNFRSF25, TNFRSF25, TNFRSF25 , TNFRSF25 , APO3, APO3, APO3 , APO3 , DDR3, DDR3, DDR3 , DDR3 , DR3, DR3, DR3 , DR3 , TNFRSF12, TNFRSF12, TNFRSF12 , TNFRSF12 , WSL, WSL, WSL , WSL , WSL1, WSL1, WSL1 , WSL1 , Tumor necrosis factor receptor superfamily member 25, Tumor necrosis factor receptor superfamily member 25, Tumor necrosis factor receptor superfamily member 25 , Tumor necrosis factor receptor superfamily member 25 , Apo-3, Apo-3, Apo-3 , Apo-3 , Apoptosis-inducing receptor AIR, Apoptosis-inducing receptor AIR, Apoptosis-inducing receptor AIR , Apoptosis-inducing receptor AIR , Apoptosis-mediating |
Gene, Accession # | UniProt: Q93038 |
Catalog # | abx029478 |
Price | please inquire |
Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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