Beta-Amyloid Precursor Protein Phospho-Thr743 (APP pT743) Antibody from ABBEXA LTD

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Antigenic SpecificityBeta-Amyloid Precursor Protein Phospho-Thr743 (APP pT743)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB
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DescriptionAPP (pT743) antibody is a Rabbit polyclonal antibody against APP (pT743). This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
ImmunogenSynthetic Peptide. A phospho specific peptide corresponding to residues surrounding T743 of human APP.
Other NamesAPP, Amyloid Beta Precursor Protein, Alpha-SAPP, AD1, Alzheimer Disease Amyloid A4 Protein Homolog, Amyloid Beta (A4) Precursor Protein, Alzheimer Disease Amyloid Protein, Cerebral Vascular Amyloid Peptide, Amyloid-Beta Precursor Protein, Amyloid Precursor Protein, Peptidase Nexin-II, Protease Nexin-II, PN-II, PreA4, ABPP, APPI, CVAP, Amyloid-Beta (A4) Precursor Protein, Beta-Amyloid Precursor Protein, Testicular Tissue Protein Li, Beta-Amyloid Peptide(1-40), Beta-Amyloid Peptide(1-42), Amyloid Beta A4 Protein, Amyloid-Beta A4 Protein, Beta-Amyloid Peptide, Alzheimer Disease, CTFgamma, ABETA, AAA, PN2, A4, N-APP, Soluble APP-Beta, Soluble APP-Alpha, APP, APP, APP , APP , Amyloid Beta Precursor Protein, Amyloid Beta Precursor Protein, Amyloid Beta Precursor Protein , Amyloid Beta Precursor Protein , Alpha-SAPP, Alpha-SAPP, Alpha-SAPP , Alpha-SAPP , AD1, AD1, AD1 , AD1 , Alzheimer Disease Amyloid A4 Protein Homolog, Alzheimer Disease Amyloid A4 Protein Homolog, Alzheimer Disease Amy
Gene, Accession #APP, Gene ID: 4609, UniProt: P05067
Catalog #abx000096
Priceplease inquire
Order / More InfoBeta-Amyloid Precursor Protein Phospho-Thr743 (APP pT743) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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