Cytochrome P450 2D6 (CYP2D6) Antibody from ABBEXA LTD

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Antigenic SpecificityCytochrome P450 2D6 (CYP2D6)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC
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DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ImmunogenKLH-conjugated synthetic peptide between 76-105 amino acids from the N-terminal region of human CYP2D6.
Other NamesCYP2D, P450C2D, CPD6, CYP2DL1, P450-DB1, Cytochrome P450 Family 2 Subfamily D Polypeptide 6, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450DB1, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 2D6, CYP2D, CYP2D, CYP2D , CYP2D , P450C2D, P450C2D, P450C2D , P450C2D , CPD6, CPD6, CPD6 , CPD6 , CYP2DL1, CYP2DL1, CYP2DL1 , CYP2DL1 , P450-DB1, P450-DB1, P450-DB1 , P450-DB1 , Cytochrome P450 Family 2 Subfamily D Polypeptide 6, Cytochrome P450 Family 2 Subfamily D Polypeptide 6, Cytochrome P450 Family 2 Subfamily D Polypeptide 6 , Cytochrome P450 Family 2 Subfamily D Polypeptide 6 , Cytochrome P450-DB1, Cytochrome P450-DB1, Cytochrome P450-DB1 , Cytochrome P450-DB1 , Debrisoquine 4-hydroxylase, Debrisoquine 4-hydroxylase, Debrisoquine 4-hydroxylase , Debrisoquine 4-hydroxylase , CYP2D6, CYP2D6, CYP2D6 , CYP2D6 , CYP2D7AP, CYP2D7AP, CYP2D7AP , CYP2D7AP , CYP2D7BP, CYP2D7BP, CYP2D7BP , CYP2D7BP , CY
Gene, Accession #CYP2D6, Gene ID: 1565, UniProt: P10635
Catalog #abx028111
Priceplease inquire
Order / More InfoCytochrome P450 2D6 (CYP2D6) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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