NPHS1, Nephrin (NPHS1) Antibody from ABBEXA LTD
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| Antigenic Specificity | NPHS1, Nephrin (NPHS1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NPHS1 antibody is a Rabbit polyclonal antibody against NPHS1. This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes. In Western blots, nephrin antibodies generated against the two terminal extracellular Ig domains of recombinant human nephrin recognized a 180-kDa protein in lysates of human glomeruli and a 150-kDa protein in transfected COS-7 cell lysates. |
| Immunogen | A synthetic peptide of human NPHS1. |
| Other Names | CNF, NPHN, nephrin, CNF, CNF, CNF , CNF , NPHN, NPHN, NPHN , NPHN , nephrin, nephrin, nephrin , nephrin |
| Gene, Accession # | NPHS1, Gene ID: 4868, UniProt: O60500 |
| Catalog # | abx002201 |
| Price | please inquire |
| Order / More Info | NPHS1, Nephrin (NPHS1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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