Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) antibody, protein, ELISA kits.
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| Antigenic Specificity | Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 20 µg, 50 µg, 100 µg, 200 µg+ |
| Concentration | n/a |
| Applications | ELISA, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Vascular Endothelial Growth Factor Receptor 2 (VEGFR2/KDR) antibody is a Rabbit polyclonal antibody against Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2/KDR). Recombinant Human VEGFR2 ProteinTyrosine-Protein Kinase That Acts As A Cell-Surface Receptor For Vegfa, Vegfc And VegfdPlays An Essential Role In The Regulation Of Angiogenesis, Vascular Development, Vascular Permeability, And Embryonic HematopoiesisPromotes ProlifeRation, Survival, MigRation And Differentiation Of Endothelial CellsPromotes Reorganization Of The Actin CytoskeletonIsoforms Lacking A Transmembrane Domain, Such As Isoform 2 And Isoform 3, May Function As Decoy Receptors For Vegfa, Vegfc And/Or VegfdIsoform 2 Plays An Important Role As Negative Regulator Of Vegfa- And Vegfc-Mediated Lymphangiogenesis By Limiting The Amount Of Free Vegfa And/Or Vegfc And Preventing Their Binding To Flt4Modulates Flt1 And Flt4 Signaling By Forming HeterodimersBinding Of Vascular Growth Factors To Isoform 1 Leads To The Activation Of Several Signaling CascadesActivation Of Plcg1 Leads To The Production Of The Cellular Signaling Molecules Diacylglycerol And Inositol 1,4,5-Trisphosphate And The Activation Of Protein Kinase CMediates Activation Of Mapk1/Erk2, Mapk3/Erk1 And The Map Kinase Signaling Pathway, As Well As Of The Akt1 Signaling PathwayMediates Phosphorylation Of Pik3R1, The Regulatory Subunit Of Phosphatidylinositol 3-Kinase, Reorganization Of The Actin Cytoskeleton And Activation Of Ptk2/Fak1Required For Vegfa-Mediated Induction Of Nos2 And Nos3, Leading To The Production Of The Signaling Molecule Nitric Oxide (No) By Endothelial CellsPhosphorylates Plcg1Promotes Phosphorylation Of Fyn, Nck1, Nos3, Pik3R1, Ptk2/Fak1 And Src. |
| Immunogen | Recombinant human Vascular endothelial growth factor receptor 2 protein (20-764AA). |
| Other Names | FLK1, Kinase Insert Domain Receptor, Fetal Liver Kinase 1, Protein-Tyrosine Kinase Receptor Flk-1, VEGFR2, Vascular Endothelial Growth Factor Receptor 2, Tyrosine Kinase Growth Factor Receptor, Fetal Liver Kinase-1, Soluble VEGFR2, CD309 Antigen, VEGFR-2, CD309, VEGFR, FLK-1, KDR, A Type III Receptor Tyrosine Kinase, FLK1, FLK1, FLK1 , FLK1 , Kinase Insert Domain Receptor, Kinase Insert Domain Receptor, Kinase Insert Domain Receptor , Kinase Insert Domain Receptor , Fetal Liver Kinase 1, Fetal Liver Kinase 1, Fetal Liver Kinase 1 , Fetal Liver Kinase 1 , Protein-Tyrosine Kinase Receptor Flk-1, Protein-Tyrosine Kinase Receptor Flk-1, Protein-Tyrosine Kinase Receptor Flk-1 , Protein-Tyrosine Kinase Receptor Flk-1 , VEGFR2, VEGFR2, VEGFR2 , VEGFR2 , Vascular Endothelial Growth Factor Receptor 2, Vascular Endothelial Growth Factor Receptor 2, Vascular Endothelial Growth Factor Receptor 2 , Vascular Endothelial Growth Factor Receptor 2 , Tyrosine Kinase Growth Factor Receptor, Tyrosi |
| Gene, Accession # | KDR, Gene ID: 3791, NCBI: NP_002244.1, NM_002253.2, UniProt: P35968 |
| Catalog # | abx110345 |
| Price | please inquire |
| Order / More Info | Vascular Endothelial Growth Factor Receptor 2 / VEGFR2 (KDR) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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