Myosin Light Chain Kinase, Smooth Muscle (MYLK) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Myosin Light Chain Kinase, Smooth Muscle (MYLK) antibody, protein, ELISA kits.
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| Antigenic Specificity | Myosin Light Chain Kinase, Smooth Muscle (MYLK) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MLCK, a member of the Ser/Thr protein kinase family, is a calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments. It is a central determinant in the development of vascular permeability and tissue edema formation. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis. Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues. MLCK is probably down-regulated by phosphorylation. The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains. |
| Immunogen | KLH-conjugated synthetic peptide between 908-938 amino acids from the N-terminal region of human MLCK. |
| Other Names | MYLK, AAT7, KRP, MLCK, MLCK108, Kinase-related protein, MLCK1, Telokin, MLC kinase, MLCK210, MSTP083, MYLK1, Myosin light chain kinase, SmMLCK, MYLK, MYLK, MYLK , MYLK , AAT7, AAT7, AAT7 , AAT7 , KRP, KRP, KRP , KRP , MLCK, MLCK, MLCK , MLCK , MLCK108, MLCK108, MLCK108 , MLCK108 , Kinase-related protein, Kinase-related protein, Kinase-related protein , Kinase-related protein , MLCK1, MLCK1, MLCK1 , MLCK1 , Telokin, Telokin, Telokin , Telokin , MLC kinase, MLC kinase, MLC kinase , MLC kinase , MLCK210, MLCK210, MLCK210 , MLCK210 , MSTP083, MSTP083, MSTP083 , MSTP083 , MYLK1, MYLK1, MYLK1 , MYLK1 , Myosin light chain kinase, Myosin light chain kinase, Myosin light chain kinase , Myosin light chain kinase , SmMLCK, SmMLCK, SmMLCK , SmMLCK |
| Gene, Accession # | UniProt: Q15746 |
| Catalog # | abx033796 |
| Price | please inquire |
| Order / More Info | Myosin Light Chain Kinase, Smooth Muscle (MYLK) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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