Transcriptional Regulator ERG (ERG) Antibody from ABBEXA LTD
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| Antigenic Specificity | Transcriptional Regulator ERG (ERG) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ERG antibody is a Rabbit polyclonal antibody against ERG. This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2012]. |
| Immunogen | Recombinant protein of human ERG. |
| Other Names | ERG, erg-3, p55, v-ets erythroblastosis virus E26 oncogene like (avian), HGNC:3446, transcriptional regulator ERG (transforming protein ERG), v-ets avian erythroblastosis virus E26 oncogene related, v-ets erythroblastosis virus E26 oncogene like, v-ets er, Transcriptional regulator ERG, Transforming protein ERG, v-ets erythroblastosis virus E26 oncogene homolog (avian), ERG, ERG, ERG , ERG , erg-3, erg-3, erg-3 , erg-3 , p55, p55, p55 , p55 , v-ets erythroblastosis virus E26 oncogene like (avian), v-ets erythroblastosis virus E26 oncogene like (avian), v-ets erythroblastosis virus E26 oncogene like (avian) , v-ets erythroblastosis virus E26 oncogene like (avian) , HGNC:3446, HGNC:3446, HGNC:3446 , HGNC:3446 , transcriptional regulator ERG (transforming protein ERG), transcriptional regulator ERG (transforming protein ERG), transcriptional regulator ERG (transforming protein ERG) , transcriptional regulator ERG (transforming protein ERG) , v-ets avian erythroblastosis virus E26 on |
| Gene, Accession # | ERG, Gene ID: 2078, UniProt: P11308 |
| Catalog # | abx001152 |
| Price | please inquire |
| Order / More Info | Transcriptional Regulator ERG (ERG) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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