Cell Adhesion Molecule 1 (CADM1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Cell Adhesion Molecule 1 (CADM1) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Cell Adhesion Molecule 1 (CADM1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cell Adhesion Molecule 1 (CADM1) antibody is a Rabbit polyclonal antibody for the detection of CADM1. Mediates homophilic cell-cell adhesion in a Ca (2+) -independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca (2+) -independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa. |
| Immunogen | cell adhesion molecule 1 |
| Other Names | CADM1, Cell Adhesion Molecule 1, SYNCAM, IGSF4A, NECL2, Tumor Suppressor In Lung Cancer 1, Necl-2, RA175, IGSF4, TSLC1, ST17, BL2, Spermatogenic Immunoglobulin Superfamily, Immunoglobulin Superfamily Member 4, Synaptic Cell Adhesion Molecule, Nectin-Like Protein 2, Nectin-Like 2, SYNCAM1, TSLC-1, Immunoglobulin Superfamily, Member 4, TSLC1/Nectin-Like 2/IGSF4, STSLC-1, SynCAM1, SgIGSF, NECL-2, SgIgSF, SynCAM, IgSF4, CADM1, CADM1, CADM1 , CADM1 , Cell Adhesion Molecule 1, Cell Adhesion Molecule 1, Cell Adhesion Molecule 1 , Cell Adhesion Molecule 1 , SYNCAM, SYNCAM, SYNCAM , SYNCAM , IGSF4A, IGSF4A, IGSF4A , IGSF4A , NECL2, NECL2, NECL2 , NECL2 , Tumor Suppressor In Lung Cancer 1, Tumor Suppressor In Lung Cancer 1, Tumor Suppressor In Lung Cancer 1 , Tumor Suppressor In Lung Cancer 1 , Necl-2, Necl-2, Necl-2 , Necl-2 , RA175, RA175, RA175 , RA175 , IGSF4, IGSF4, IGSF4 , IGSF4 , TSLC1, TSLC1, TSLC1 , TSLC1 , ST17, ST17, ST17 , ST17 , BL2, BL2, BL2 , BL2 , Spermatogenic Immuno |
| Gene, Accession # | CADM1, Gene ID: 23705, UniProt: Q9BY67 |
| Catalog # | abx146655 |
| Price | please inquire |
| Order / More Info | Cell Adhesion Molecule 1 (CADM1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies