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Antigenic Specificity | FYVE, RhoGEF And PH Domain-Containing Protein 4 (FGD4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 157-186 amino acids from the N-terminal region of human FGD4. |
Other Names | FGD4, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain-containing protein 4, Actin filament-binding protein frabin, FGD1-related F-actin-binding protein, Zinc finger FYVE domain-containing protein 6, FGD4, FGD4, FGD4 , FGD4 , FRABP, FRABP, FRABP , FRABP , ZFYVE6, ZFYVE6, ZFYVE6 , ZFYVE6 , FYVE, FYVE, FYVE , FYVE , RhoGEF and PH domain-containing protein 4, RhoGEF and PH domain-containing protein 4, RhoGEF and PH domain-containing protein 4 , RhoGEF and PH domain-containing protein 4 , Actin filament-binding protein frabin, Actin filament-binding protein frabin, Actin filament-binding protein frabin , Actin filament-binding protein frabin , FGD1-related F-actin-binding protein, FGD1-related F-actin-binding protein, FGD1-related F-actin-binding protein , FGD1-related F-actin-binding protein , Zinc finger FYVE domain-containing protein 6, Zinc finger FYVE domain-containing protein 6, Zinc finger FYVE domain-containing protein 6 , Zinc finger FYVE domain-containing protein 6 |
Gene, Accession # | FGD4, UniProt: Q96M96 |
Catalog # | abx027128 |
Price | please inquire |
Order / More Info | FYVE, RhoGEF And PH Domain-Containing Protein 4 (FGD4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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