MAP3K7IP1 (pS423) Antibody from ABBEXA LTD
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| Antigenic Specificity | MAP3K7IP1 (pS423) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, DB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MAP3K7IP1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S423 of human MAP3K7IP1. |
| Other Names | MAP3K7IP1, Mitogen Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1, mitogen-activated protein kinase kinase kinase 7 interacting protein 1, 3-Tab1, MGC57664, TAB1, 3'-Tab1, MAP3K7IP1, MAP3K7IP1, MAP3K7IP1 , MAP3K7IP1 , Mitogen Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1, Mitogen Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1, Mitogen Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1 , Mitogen Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1 , mitogen-activated protein kinase kinase kinase 7 interacting protein 1, mitogen-activated protein kinase kinase kinase 7 interacting protein 1, mitogen-activated protein kinase kinase kinase 7 interacting protein 1 , mitogen-activated protein kinase kinase kinase 7 interacting protein 1 , 3-Tab1, 3-Tab1, 3-Tab1 , 3-Tab1 , MGC57664, MGC57664, MGC57664 , MGC57664 , TAB1, TAB1, TAB1 , TAB1 , 3'-Tab1, 3'-Tab1, 3'-Tab1 , 3'-Tab1 |
| Gene, Accession # | UniProt: Q15750 |
| Catalog # | abx031978 |
| Price | please inquire |
| Order / More Info | MAP3K7IP1 (pS423) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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