SUMO-Activating Enzyme Subunit 2 (SAE2) Antibody from ABBEXA LTD
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| Antigenic Specificity | SUMO-Activating Enzyme Subunit 2 (SAE2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ubiquitin is covalently attached to target proteins by a multienzymatic system consisting of E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-ligating) enzymes. NEDD8, a ubiquitin-like protein, is conjugated to proteins in a manner analogous to ubiquitinylation. beta-amyloid precursor protein-binding protein-1 (APPBP1) can bind to NEDD8 in rabbit reticulocyte lysates. However, since APPBP1 shows similarity to only the N-terminal domain of an E1 enzyme, it must interact with a protein showing similarity to the C-terminal region of E1s. By searching sequence databases, a cDNAs encoding UBA3 was identified as the human homolog of yeast Uba3. The predicted 442-amino acid UBA3 protein shares 43% sequence identity with yeast Uba3. In vitro, UBA3 formed a complex with APPBP1 and a thioester linkage with NEDD8. APPBP1/UBA3 complex may function as an E1-like enzyme for the activation of NEDD8. |
| Immunogen | KLH-conjugated synthetic peptide between 601-631 amino acids from the C-terminal region of human SAE2 (UBA2). |
| Other Names | UBA2, SAE2, UBLE1B, SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, UBA2, UBA2, UBA2 , UBA2 , SAE2, SAE2, SAE2 , SAE2 , UBLE1B, UBLE1B, UBLE1B , UBLE1B , SUMO-activating enzyme subunit 2, SUMO-activating enzyme subunit 2, SUMO-activating enzyme subunit 2 , SUMO-activating enzyme subunit 2 , Anthracycline-associated resistance ARX, Anthracycline-associated resistance ARX, Anthracycline-associated resistance ARX , Anthracycline-associated resistance ARX , Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like 1-activating enzyme E1B , Ubiquitin-like 1-activating enzyme E1B |
| Gene, Accession # | UniProt: Q9UBT2 |
| Catalog # | abx025828 |
| Price | please inquire |
| Order / More Info | SUMO-Activating Enzyme Subunit 2 (SAE2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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