Cystatin C (CST3) Antibody from ABBEXA LTD

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Antigenic SpecificityCystatin C (CST3)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. (provided by RefSeq)Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
ImmunogenPurified recombinant fragment of human CST3 expressed in E. Coli.
Other NamesCST3, Cystatin C, Neuroendocrine Basic Polypeptide, Post-Gamma-Globulin, Gamma-Trace, Cystatin C (Amyloid Angiopathy And Cerebral Hemorrhage), Epididymis Secretory Protein Li 2, BA218C14.4 (Cystatin C), Cystatin 3, Cystatin-C, Cystatin-3, Cys-C, Gamma Trace, Amyloid Angiopathy And Cerebral Hemorrhage, HEL-S-2, ARMD11, CST3, CST3, CST3 , CST3 , Cystatin C, Cystatin C, Cystatin C , Cystatin C , Neuroendocrine Basic Polypeptide, Neuroendocrine Basic Polypeptide, Neuroendocrine Basic Polypeptide , Neuroendocrine Basic Polypeptide , Post-Gamma-Globulin, Post-Gamma-Globulin, Post-Gamma-Globulin , Post-Gamma-Globulin , Gamma-Trace, Gamma-Trace, Gamma-Trace , Gamma-Trace , Cystatin C (Amyloid Angiopathy And Cerebral Hemorrhage), Cystatin C (Amyloid Angiopathy And Cerebral Hemorrhage), Cystatin C (Amyloid Angiopathy And Cerebral Hemorrhage) , Cystatin C (Amyloid Angiopathy And Cerebral Hemorrhage) , Epididymis Secretory Protein Li 2, Epididymis Secretory Protein Li 2, Epididymis Secretor
Gene, Accession #CST3, Gene ID: 1471, UniProt: P01034
Catalog #abx011640
Priceplease inquire
Order / More InfoCystatin C (CST3) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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