Hepatocyte Growth Factor (HGF) Antibody from ABBEXA LTD

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Antigenic SpecificityHepatocyte Growth Factor (HGF)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionHepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq].
ImmunogenKLH-conjugated synthetic peptide between 521-554 amino acids from human HGF.
Other NamesHepatocyte Growth Factor, HGF, Hepatopoietin-A, Hepatopoietin A, Scatter Factor, HPTA, SF, Lung Fibroblast-Derived Mitogen, DFNB39, F-TCF, HGFB, Hepapoietin A, Fibroblast-Derived Tumor Cytotoxic Factor, Hepatocyte Growth Factor, Hepatocyte Growth Factor, Hepatocyte Growth Factor , Hepatocyte Growth Factor , HGF, HGF, HGF , HGF , Hepatopoietin-A, Hepatopoietin-A, Hepatopoietin-A , Hepatopoietin-A , Hepatopoietin A, Hepatopoietin A, Hepatopoietin A , Hepatopoietin A , Scatter Factor, Scatter Factor, Scatter Factor , Scatter Factor , HPTA, HPTA, HPTA , HPTA , SF, SF, SF , SF , Lung Fibroblast-Derived Mitogen, Lung Fibroblast-Derived Mitogen, Lung Fibroblast-Derived Mitogen , Lung Fibroblast-Derived Mitogen , DFNB39, DFNB39, DFNB39 , DFNB39 , F-TCF, F-TCF, F-TCF , F-TCF , HGFB, HGFB, HGFB , HGFB , Hepapoietin A, Hepapoietin A, Hepapoietin A , Hepapoietin A , Fibroblast-Derived Tumor Cytotoxic Factor, Fibroblast-Derived Tumor Cytotoxic Factor, Fibroblast-Derived Tumor Cytotoxic
Gene, Accession #UniProt: P14210
Catalog #abx025437
Priceplease inquire
Order / More InfoHepatocyte Growth Factor (HGF) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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