Edit |   |
---|---|
Antigenic Specificity | Hepatocyte Growth Factor (HGF) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 521-554 amino acids from human HGF. |
Other Names | Hepatocyte Growth Factor, HGF, Hepatopoietin-A, Hepatopoietin A, Scatter Factor, HPTA, SF, Lung Fibroblast-Derived Mitogen, DFNB39, F-TCF, HGFB, Hepapoietin A, Fibroblast-Derived Tumor Cytotoxic Factor, Hepatocyte Growth Factor, Hepatocyte Growth Factor, Hepatocyte Growth Factor , Hepatocyte Growth Factor , HGF, HGF, HGF , HGF , Hepatopoietin-A, Hepatopoietin-A, Hepatopoietin-A , Hepatopoietin-A , Hepatopoietin A, Hepatopoietin A, Hepatopoietin A , Hepatopoietin A , Scatter Factor, Scatter Factor, Scatter Factor , Scatter Factor , HPTA, HPTA, HPTA , HPTA , SF, SF, SF , SF , Lung Fibroblast-Derived Mitogen, Lung Fibroblast-Derived Mitogen, Lung Fibroblast-Derived Mitogen , Lung Fibroblast-Derived Mitogen , DFNB39, DFNB39, DFNB39 , DFNB39 , F-TCF, F-TCF, F-TCF , F-TCF , HGFB, HGFB, HGFB , HGFB , Hepapoietin A, Hepapoietin A, Hepapoietin A , Hepapoietin A , Fibroblast-Derived Tumor Cytotoxic Factor, Fibroblast-Derived Tumor Cytotoxic Factor, Fibroblast-Derived Tumor Cytotoxic |
Gene, Accession # | UniProt: P14210 |
Catalog # | abx025437 |
Price | please inquire |
Order / More Info | Hepatocyte Growth Factor (HGF) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950