Mitogen-Activated Protein Kinase 14 Phospho-Thr180/Tyr182 (MAPK14 pT180/Y182) Antibody from ABBEXA LTD
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| Antigenic Specificity | Mitogen-Activated Protein Kinase 14 Phospho-Thr180/Tyr182 (MAPK14 pT180/Y182) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mitogen-Activated Protein Kinase 14 Phospho-Thr180/Tyr182 (MAPK14 pT180/Y182) antibody is a Rabbit polyclonal antibody for the detection of Phospho- MAPK14 (T180/Y182). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Immunogen | A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK |
| Other Names | CRK1, CSAID binding protein, CSBP, CSBP1, CSBP2, Cytokine suppressive anti inflammatory drug binding protein, MAP kinase MXI2, MAP kinase p38, MAPK14, MAX-interacting protein 2, MK14, MXI2, CRK1, CRK1, CRK1 , CRK1 , CSAID binding protein, CSAID binding protein, CSAID binding protein , CSAID binding protein , CSBP, CSBP, CSBP , CSBP , CSBP1, CSBP1, CSBP1 , CSBP1 , CSBP2, CSBP2, CSBP2 , CSBP2 , Cytokine suppressive anti inflammatory drug binding protein, Cytokine suppressive anti inflammatory drug binding protein, Cytokine suppressive anti inflammatory drug binding protein , Cytokine suppressive anti inflammatory drug binding protein , MAP kinase MXI2, MAP kinase MXI2, MAP kinase MXI2 , MAP kinase MXI2 , MAP kinase p38, MAP kinase p38, MAP kinase p38 , MAP kinase p38 , MAPK14, MAPK14, MAPK14 , MAPK14 , MAX-interacting protein 2, MAX-interacting protein 2, MAX-interacting protein 2 , MAX-interacting protein 2 , MK14, MK14, MK14 , MK14 , MXI2, MXI2, MXI2 , MXI2 |
| Gene, Accession # | MAPK14, Gene ID: 1432, UniProt: Q16539 |
| Catalog # | abx020091 |
| Price | please inquire |
| Order / More Info | Mitogen-Activated Protein Kinase 14 Phospho-Thr180/Tyr182 (MAPK14 pT180/Y182) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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