MAP2K2 (pT394) Antibody from ABBEXA LTD

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Antigenic SpecificityMAP2K2 (pT394)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size50 µl, 100 µl, 200 µl,
Concentration> 0.5 mg/ml
ApplicationsWB, IHC, IF/ICC
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DescriptionMAP2K2 (pT394) antibody is a Rabbit polyclonal antibody against MAP2K2 (pT394). The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
ImmunogenSynthetic Peptide. A phospho specific peptide corresponding to residues surrounding T394 of human MAP2K2.
Other NamesMAP2K2, mitogen-activated protein kinase kinase 2, MAPKK2, MEK2, MKK2, PRKMK2, ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, dual specificity mitogen-activated protein kinase kinase 2, mitogen-activated protein kinase kinase 2, p45, MAP2K2, MAP2K2, MAP2K2 , MAP2K2 , mitogen-activated protein kinase kinase 2, mitogen-activated protein kinase kinase 2, mitogen-activated protein kinase kinase 2 , mitogen-activated protein kinase kinase 2 , MAPKK2, MAPKK2, MAPKK2 , MAPKK2 , MEK2, MEK2, MEK2 , MEK2 , MKK2, MKK2, MKK2 , MKK2 , PRKMK2, PRKMK2, PRKMK2 , PRKMK2 , ERK activator kinase 2, ERK activator kinase 2, ERK activator kinase 2 , ERK activator kinase 2 , MAP kinase kinase 2, MAP kinase kinase 2, MAP kinase kinase 2 , MAP kinase kinase 2 , MAPK/ERK kinase 2, MAPK/ERK kinase 2, MAPK/ERK kinase 2 , MAPK/ERK kinase 2 , dual specificity mitogen-activated protein kinase kinase 2, dual specificity mitogen-activated protein kinase kinase 2, dual specificity mitogen-acti
Gene, Accession #MAP2K2, Gene ID: 5605, UniProt: P36507
Catalog #abx000173
Priceplease inquire
Order / More InfoMAP2K2 (pT394) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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