TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) antibody, protein, ELISA kits.
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| Antigenic Specificity | TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 100 µl, |
| Concentration | 1 mg/ml |
| Applications | ELISA, WB, IF/ICC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF- kappa B, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described. The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. |
| Immunogen | Purified recombinant fragment of human FAS expressed in E. Coli. |
| Other Names | FAS, Fas Cell Surface Death Receptor, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily Member 6, Fas (TNF Receptor Superfamily, Member 6), Apoptosis-Mediating Surface Antigen FAS, TNF Receptor Superfamily Member 6, FASLG Receptor, CD95 Antigen, TNFRSF6, APT1, FAS1, Mutant Tumor Necrosis Receptor Superfamily Member 6, Apoptosis Signaling Receptor FAS, APO-1 Cell Surface Antigen, Apoptosis Antigen 1, Apo-1 Antigen, Fas AMA, ALPS1A, APO-1, FASTM, CD95, Factor Related Apoptosis, FAS, FAS, FAS , FAS , Fas Cell Surface Death Receptor, Fas Cell Surface Death Receptor, Fas Cell Surface Death Receptor , Fas Cell Surface Death Receptor , Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily, Member 6, Tumor Necrosis Factor Receptor Superfamily, Member 6 , Tumor Necrosis Factor Receptor Superfamily, Member 6 , Tumor Necrosis Factor Receptor Superfamily Member 6, Tumor Necrosis Factor Receptor Superfamil |
| Gene, Accession # | FAS, Gene ID: 355, UniProt: P25445 |
| Catalog # | abx011831 |
| Price | please inquire |
| Order / More Info | TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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