Tight Junction Protein ZO-1 (TJP1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Tight Junction Protein ZO-1 (TJP1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Tight Junction Protein ZO-1 (TJP1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | 1.26 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TJP1 Antibody is a Rabbit Polyclonal antibody against TJP1 (ZO1). Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane proteins between the apical and the basolateral cell surfaces (reviewed in 1). Zona occludens proteins ZO-1, -2, and -3 (also known as TJP1, 2, and 3) are peripheral membrane adaptor proteins that link junctional transmembrane proteins such as occludin and claudin to the actin cytoskeleton (reviewed in 2). ZO-1 and -2 are required for tight junction formation and function (3,4). In subconfluent proliferating cells, ZO-1 and ZO-2 have been shown to colocalize to the nucleus and play a role in transcriptional regulation, possibly through facilitating nuclear import/export of transcriptional regulators (5-7). The ZO-2 gene is transcribed from two promoters, generating the ZO-2A and ZO-2C isoforms. ZO-2C lacks a 23 amino acid amino-terminal sequence found in other ZO-2 isoforms. While both isoforms appear to be widely expressed, abnormal regulation of the ZO-2 gene may be correlated with development of ductal cancer (8). |
| Immunogen | Recombinant fusion protein of human ZO1. |
| Other Names | TJP1, tight junction protein 1 (zona occludens 1), DKFZp686M05161, MGC133289, ZO-1, OTTHUMP00000174520, tight junction protein 1, tight junction protein ZO-1, zona occludens 1, zonula occludens 1 protein, Zona occludens protein 1, ZO1, TJP1, TJP1, TJP1, TJP1, tight junction protein 1 (zona occludens 1), tight junction protein 1 (zona occludens 1), tight junction protein 1 (zona occludens 1), tight junction protein 1 (zona occludens 1), DKFZp686M05161, DKFZp686M05161, DKFZp686M05161, DKFZp686M05161, MGC133289, MGC133289, MGC133289, MGC133289, ZO-1, ZO-1, ZO-1, ZO-1, OTTHUMP00000174520, OTTHUMP00000174520, OTTHUMP00000174520, OTTHUMP00000174520, tight junction protein 1, tight junction protein 1, tight junction protein 1, tight junction protein 1, tight junction protein ZO-1, tight junction protein ZO-1, tight junction protein ZO-1, tight junction protein ZO-1, zona occludens 1, zona occludens 1, zona occludens 1, zona occludens 1, zonula occludens 1 protein, zonula occludens 1 protein, zonula occludens 1 protein, zonula occludens 1 protein, Zona occludens protein 1, Zona occludens protein 1, Zona occludens protein 1, Zona occludens protein 1, ZO1, ZO1, ZO1, ZO1 |
| Gene, Accession # | TJP1, Gene ID: 7082, UniProt: Q07157 |
| Catalog # | abx000800 |
| Price | please inquire |
| Order / More Info | Tight Junction Protein ZO-1 (TJP1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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