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Antigenic Specificity | Insulin Like Growth Factor 1 Receptor (IGF1R) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Rabbit Polyclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R). Insulin Like Growth Factor 1 Receptor (IGF1R), also named as CD221, belongs to the protein kinase superfamily, Tyr protein kinase family and Insulin receptor subfamily. Insulin Like Growth Factor 1 Receptor (IGF1R) binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, Insulin Like Growth Factor 1 Receptor (IGF1R) binds IGF1. The hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, the hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Long and hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin. Defects in Insulin Like Growth Factor 1 Receptor (IGF1R) may be a cause in some cases of resistance to insulin-like growth factor 1 (IGF1 resistance). The antibody is specific to Insulin Like Growth Factor 1 Receptor (IGF1R). |
Immunogen | Synthetic peptide. N term -peptide of human IGF1R. |
Other Names | IGF1R, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I Receptor, CD221 Antigen, CD221, IGFIR, JTK13, IGFR, Soluble IGF1R Variant 1, Soluble IGF1R Variant 2, IGF-1 Receptor, Insulin Like Growth Factor 1 Receptor, IGF-1R, IGF1-R, IGF-1R r, IGF1R, IGF1R, IGF1R, IGF1R, Insulin-like growth factor 1 receptor, Insulin-like growth factor 1 receptor, Insulin-like growth factor 1 receptor, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, Insulin-like growth factor I receptor, Insulin-like growth factor I receptor, Insulin-like growth factor I receptor, IGF-I Receptor, IGF-I Receptor, IGF-I Receptor, IGF-I Receptor, CD221 Antigen, CD221 Antigen, CD221 Antigen, CD221 Antigen, CD221, CD221, CD221, CD221, IGFIR, IGFIR, IGFIR, IGFIR, JTK13, JTK13, JTK13, JTK13, IGFR, IGFR, IGFR, IGFR, Soluble IGF1R Variant 1, Soluble IGF1R Variant 1, Soluble IGF1R Variant 1, Soluble IGF1R Variant 1, Soluble IGF1R Variant 2, Soluble IGF1R Variant 2, Soluble IGF1R Variant 2, Soluble IGF1R Variant 2, IGF-1 Receptor, IGF-1 Receptor, IGF-1 Receptor, IGF-1 Receptor, Insulin Like Growth Factor 1 Receptor, Insulin Like Growth Factor 1 Receptor, Insulin Like Growth Factor 1 Receptor, Insulin Like Growth Factor 1 Receptor, IGF-1R, IGF-1R, IGF-1R, IGF-1R, IGF1-R, IGF1-R, IGF1-R, IGF1-R, IGF-1R r, IGF-1R r, IGF-1R r, IGF-1R r |
Gene, Accession # | IGF1R, Gene ID: 3480, UniProt: P08069 |
Catalog # | abx000628 |
Price | please inquire |
Order / More Info | Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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