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Antigenic Specificity | Cathepsin F (CTSF) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF is a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. |
Immunogen | KLH-conjugated synthetic peptide between 261-290 amino acids from the Central region of human CTSF. |
Other Names | CTSF, Cathepsin F, CTSF, CTSF, CTSF , CTSF , Cathepsin F, Cathepsin F, Cathepsin F , Cathepsin F |
Gene, Accession # | UniProt: Q9UBX1 |
Catalog # | abx032874 |
Price | please inquire |
Order / More Info | Cathepsin F (CTSF) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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