PTK2B (pY402) Antibody from ABBEXA LTD
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| Antigenic Specificity | PTK2B (pY402) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl, |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PTK2B (pY402) antibody is a Rabbit polyclonal antibody against PTK2B (pY402). This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y402 of human PTK2B. |
| Other Names | PKB, PTK, CAKB, FAK2, PYK2, CADTK, FADK2, RAFTK, Ptk2b, Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, PKB, PKB, PKB , PKB , PTK, PTK, PTK , PTK , CAKB, CAKB, CAKB , CAKB , FAK2, FAK2, FAK2 , FAK2 , PYK2, PYK2, PYK2 , PYK2 , CADTK, CADTK, CADTK , CADTK , FADK2, FADK2, FADK2 , FADK2 , RAFTK, RAFTK, RAFTK , RAFTK , Ptk2b, Ptk2b, Ptk2b , Ptk2b , Protein-tyrosine kinase 2-beta, Protein-tyrosine kinase 2-beta, Protein-tyrosine kinase 2-beta , Protein-tyrosine kinase 2-beta , Calcium-dependent tyrosine kinase, Calcium-dependent tyrosine kinase, Calcium-dependent tyrosine kinase , Calcium-dependent tyrosine kinase , Calcium-regulated non-receptor proline-rich tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, Calcium-regulated non-receptor proline-rich |
| Gene, Accession # | PTK2B, Gene ID: 2185, UniProt: Q14289 |
| Catalog # | abx000266 |
| Price | please inquire |
| Order / More Info | PTK2B (pY402) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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