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Antigenic Specificity | Myelin Protein Zero Like 2 (MPZL2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 67-94 amino acids from the Central region of human MPZL2. |
Other Names | MPZL2, EVA, EVA1, Myelin protein zero-like protein 2, Epithelial V-like antigen 1, UNQ606/PRO1192, MPZL2, MPZL2, MPZL2 , MPZL2 , EVA, EVA, EVA , EVA , EVA1, EVA1, EVA1 , EVA1 , Myelin protein zero-like protein 2, Myelin protein zero-like protein 2, Myelin protein zero-like protein 2 , Myelin protein zero-like protein 2 , Epithelial V-like antigen 1, Epithelial V-like antigen 1, Epithelial V-like antigen 1 , Epithelial V-like antigen 1 , UNQ606/PRO1192, UNQ606/PRO1192, UNQ606/PRO1192 , UNQ606/PRO1192 |
Gene, Accession # | MPZL2, UniProt: O60487 |
Catalog # | abx029723 |
Price | please inquire |
Order / More Info | Myelin Protein Zero Like 2 (MPZL2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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