Hyaluronan Synthase 1 (HAS1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Hyaluronan Synthase 1 (HAS1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Hyaluronan Synthase 1 (HAS1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. |
| Immunogen | KLH-conjugated synthetic peptide between 166-193 amino acids from the Central region of human HAS1. |
| Other Names | HAS, HAS1, Hyaluronan synthase 1, Hyaluronate synthase 1, Hyaluronic acid synthase 1, HAS, HAS, HAS , HAS , HAS1, HAS1, HAS1 , HAS1 , Hyaluronan synthase 1, Hyaluronan synthase 1, Hyaluronan synthase 1 , Hyaluronan synthase 1 , Hyaluronate synthase 1, Hyaluronate synthase 1, Hyaluronate synthase 1 , Hyaluronate synthase 1 , Hyaluronic acid synthase 1, Hyaluronic acid synthase 1, Hyaluronic acid synthase 1 , Hyaluronic acid synthase 1 |
| Gene, Accession # | UniProt: Q92839 |
| Catalog # | abx032347 |
| Price | please inquire |
| Order / More Info | Hyaluronan Synthase 1 (HAS1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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