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Antigenic Specificity | Complement Factor B (CFB) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | 3.12 mg/ml |
Applications | WB, IHC, IF/ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CFB Antibody is a Rabbit Polyclonal antibody against CFB. This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5? end of the gene for complement component 2. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 80-420 of human Complement Factor B. |
Other Names | CFB, Complement Factor B, B-Factor, Properdin, Properdin Factor B, C3/C5 Convertase, PBF2, BFD, GBG, BF, Glycine-Rich Beta-Glycoprotein, Glycine-Rich Beta Glycoprotein, C3 Proaccelerator, C3 Proactivator, EC 3.4.21.47, ARMD14, AHUS4, FBI12, H2-Bf, CFAB, CFBD, FB, CFB, CFB, CFB, CFB, Complement Factor B, Complement Factor B, Complement Factor B, Complement Factor B, B-Factor, Properdin, B-Factor, Properdin, B-Factor, Properdin, B-Factor, Properdin, Properdin Factor B, Properdin Factor B, Properdin Factor B, Properdin Factor B, C3/C5 Convertase, C3/C5 Convertase, C3/C5 Convertase, C3/C5 Convertase, PBF2, PBF2, PBF2, PBF2, BFD, BFD, BFD, BFD, GBG, GBG, GBG, GBG, BF, BF, BF, BF, Glycine-Rich Beta-Glycoprotein, Glycine-Rich Beta-Glycoprotein, Glycine-Rich Beta-Glycoprotein, Glycine-Rich Beta-Glycoprotein, Glycine-Rich Beta Glycoprotein, Glycine-Rich Beta Glycoprotein, Glycine-Rich Beta Glycoprotein, Glycine-Rich Beta Glycoprotein, C3 Proaccelerator, C3 Proaccelerator, C3 Proaccelerator, C3 Proaccelerator, C3 Proactivator, C3 Proactivator, C3 Proactivator, C3 Proactivator, EC 3.4.21.47, EC 3.4.21.47, EC 3.4.21.47, EC 3.4.21.47, ARMD14, ARMD14, ARMD14, ARMD14, AHUS4, AHUS4, AHUS4, AHUS4, FBI12, FBI12, FBI12, FBI12, H2-Bf, H2-Bf, H2-Bf, H2-Bf, CFAB, CFAB, CFAB, CFAB, CFBD, CFBD, CFBD, CFBD, FB, FB, FB, FB |
Gene, Accession # | CFB, Gene ID: 629, NCBI Accession: NP_001701.2, UniProt: P00751 |
Catalog # | abx001430 |
Price | please inquire |
Order / More Info | Complement Factor B (CFB) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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