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Antigenic Specificity | Ewing Sarcoma Breakpoint Region 1 (EWSR1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t (11;22) (q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 623-652 amino acids from the C-terminal region of human EWSR1. |
Other Names | EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS, bK984G1.4, Ewing sarcoma breakpoint region 1, EWS/FLI fusion protein, EWSR1/ZNF384 fusion protein, Ewings sarcoma EWS-Fli1 (type 1) oncogene, bK984G1.4 (Ewing sarcoma breakpoint region 1 protein), extraskeletal myxoid chondrosarcoma EWS/TEC/CHN fusion pr, RNA-binding protein EWS, EWS oncogene, EWS oncogene, EWS oncogene , EWS oncogene , Ewing sarcoma breakpoint region 1 protein, Ewing sarcoma breakpoint region 1 protein, Ewing sarcoma breakpoint region 1 protein , Ewing sarcoma breakpoint region 1 protein , EWSR1, EWSR1, EWSR1 , EWSR1 , EWS, EWS, EWS , EWS , bK984G1.4, bK984G1.4, bK984G1.4 , bK984G1.4 , Ewing sarcoma breakpoint region 1, Ewing sarcoma breakpoint region 1, Ewing sarcoma breakpoint region 1 , Ewing sarcoma breakpoint region 1 , EWS/FLI fusion protein, EWS/FLI fusion protein, EWS/FLI fusion protein , EWS/FLI fusion protein , EWSR1/ZNF384 fusion protein, EWSR1/ZNF384 fusion protein, EWSR1/ZNF384 f |
Gene, Accession # | NCBI: NP_001156757.1, NP_001156758.1, NP_001156759.1, NP_005234.1, NP_053733.2, UniProt: Q01844 |
Catalog # | abx028153 |
Price | please inquire |
Order / More Info | Ewing Sarcoma Breakpoint Region 1 (EWSR1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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