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Antigenic Specificity | SATB Homeobox 2 (SATB2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SATB Homeobox 2 (SATB2) antibody is a Rabbit polyclonal antibody for the detection of SATB2. Binds to DNA, at nuclear matrix-or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. |
Immunogen | SATB homeobox 2 |
Other Names | DNA binding protein SATB2, KIAA1034, SATB homeobox 2, SATB2, DNA binding protein SATB2, DNA binding protein SATB2, DNA binding protein SATB2 , DNA binding protein SATB2 , KIAA1034, KIAA1034, KIAA1034 , KIAA1034 , SATB homeobox 2, SATB homeobox 2, SATB homeobox 2 , SATB homeobox 2 , SATB2, SATB2, SATB2 , SATB2 |
Gene, Accession # | UniProt: Q9UPW6 |
Catalog # | abx218442 |
Price | please inquire |
Order / More Info | SATB Homeobox 2 (SATB2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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