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Antigenic Specificity | Bcl2-Related protein A1 (BCL2A1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero or homodimers and act as anti and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. |
Immunogen | KLH-conjugated synthetic peptide between 53-81 amino acids from the Central region of human BCL2A1. |
Other Names | BCL2A1, ACC-1, ACC-2, Bcl-2-like protein 5, Bcl-2-related protein A1, BCL2-related protein A1, BFL1, Bcl2-L-5, BCL2L5, GRS, HBPA1, Protein BFL-1, Protein GRS, Hemopoietic-specific early response protein, hematopoietic BCL2-related protein A1, BCL2A1, BCL2A1, BCL2A1 , BCL2A1 , ACC-1, ACC-1, ACC-1 , ACC-1 , ACC-2, ACC-2, ACC-2 , ACC-2 , Bcl-2-like protein 5, Bcl-2-like protein 5, Bcl-2-like protein 5 , Bcl-2-like protein 5 , Bcl-2-related protein A1, Bcl-2-related protein A1, Bcl-2-related protein A1 , Bcl-2-related protein A1 , BCL2-related protein A1, BCL2-related protein A1, BCL2-related protein A1 , BCL2-related protein A1 , BFL1, BFL1, BFL1 , BFL1 , Bcl2-L-5, Bcl2-L-5, Bcl2-L-5 , Bcl2-L-5 , BCL2L5, BCL2L5, BCL2L5 , BCL2L5 , GRS, GRS, GRS , GRS , HBPA1, HBPA1, HBPA1 , HBPA1 , Protein BFL-1, Protein BFL-1, Protein BFL-1 , Protein BFL-1 , Protein GRS, Protein GRS, Protein GRS , Protein GRS , Hemopoietic-specific early response protein, Hemopoietic-specific early response |
Gene, Accession # | UniProt: Q16548 |
Catalog # | abx027146 |
Price | please inquire |
Order / More Info | Bcl2-Related protein A1 (BCL2A1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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