Alpha Synuclein (SNCA) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Alpha Synuclein (SNCA) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Alpha Synuclein (SNCA) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Alpha Synuclein is implicated in the regulation of dopamine release and transport. It is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). In the nervous system, alpha Synuclein is primarily located at presynaptic terminals and is found membrane bound in dopaminergic neurons. It can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies), including Parkinson's Disease. Alpha Synuclein induces fibrillization of microtubule associated protein tau and reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase 3 activation. Alpha synuclein is a protein phosphorylated predominantly on serine residues. Additional splicing may be present but the full-length nature of these variants has not been determined. This variant (NACP112) lacks an alternate in-frame segment, compared to variant NACP140, resulting in a shorter protein (isoform NACP112) that has a distinct C-terminus, compared to isoform NACP140. This antibody recognizes both NACP112 and NCAP140. |
| Immunogen | KLH-conjugated synthetic peptide between 75-104 amino acids from the C-terminal region of human SNCA. |
| Other Names | NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, SYN, SYUA, alpha-synuclein, synuclein, alpha, PARK1, SNCA, PD1, PARK4, synuclein, alpha (non A4 component of amyloid precursor), non A-beta component of AD amyloid, synuclein alpha-140, alpha (non A4 component of amyloid precursor), MGC110988, TLR7-like, NACP, NACP, NACP , NACP , Non-A beta component of AD amyloid, Non-A beta component of AD amyloid, Non-A beta component of AD amyloid , Non-A beta component of AD amyloid , Non-A4 component of amyloid precursor, Non-A4 component of amyloid precursor, Non-A4 component of amyloid precursor , Non-A4 component of amyloid precursor , SYN, SYN, SYN , SYN , SYUA, SYUA, SYUA , SYUA , alpha-synuclein, alpha-synuclein, alpha-synuclein , alpha-synuclein , synuclein, synuclein, synuclein , synuclein , alpha, alpha, alpha , alpha , PARK1, PARK1, PARK1 , PARK1 , SNCA, SNCA, SNCA , SNCA , PD1, PD1, PD1 , PD1 , PARK4, PARK4, PARK4 , PARK4 , synuclein, alpha (no |
| Gene, Accession # | UniProt: P37840 |
| Catalog # | abx032819 |
| Price | please inquire |
| Order / More Info | Alpha Synuclein (SNCA) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies