Edit |   |
---|---|
Antigenic Specificity | Cluster Of Differentiation 14 (CD14) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cluster Of Differentiation 14 (CD14) antibody is a Rabbit polyclonal antibody for the detection of CD14. Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). |
Immunogen | CD14 molecule |
Other Names | CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, LPS-receptor, urinary form, membrane-bound form, CD antigen CD14), Monocyte differentiation antigen CD141, CD13, Pan Myeloid Cells, Cd13 Myeloid Cells, MAB TO CD13 MYELOID CELLS, CD14 antigen, CD14 molecule, Lipopolysaccharide receptor, LPSR, Monocyte Differentiation Antigen 14, Myeloid cell specific leucine rich glycoprotein, CD14 Biotin, HGNC:1628, Cd14 Monocytes, MAB TO CD14 MONOCYTES, MAb to CD14, CD14, CD14, CD14 , CD14 , Monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14 , Monocyte differentiation antigen CD14 , Myeloid cell-specific leucine-rich glycoprotein, Myeloid cell-specific leucine-rich glycoprotein, Myeloid cell-specific leucine-rich glycoprotein , Myeloid cell-specific leucine-rich glycoprotein , LPS-receptor, LPS-receptor, LPS-receptor , LPS-receptor , urinary form, urinary form, urinary form , urinary form |
Gene, Accession # | CD14, Gene ID: 929, UniProt: P08571 |
Catalog # | abx239987 |
Price | please inquire |
Order / More Info | Cluster Of Differentiation 14 (CD14) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950