Edit |   |
---|---|
Antigenic Specificity | Wilms Tumor 1 (WT1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | WT1 Antibody is a Rabbit Polyclonal antibody against WT1. This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm?s tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]. |
Immunogen | Recombinant protein of human WT1. |
Other Names | WT1, Wilms Tumor 1, WT33, Wilms Tumor Protein Isoform Ex4a(+), Wilms Tumor Protein, EWS-WT1, NPHS4, WIT-2, WAGR, AWT1, GUD, Wilms Tumor Protein 1, WT1, WT1, WT1, WT1, Wilms Tumor 1, Wilms Tumor 1, Wilms Tumor 1, Wilms Tumor 1, WT33, WT33, WT33, WT33, Wilms Tumor Protein Isoform Ex4a(+), Wilms Tumor Protein Isoform Ex4a(+), Wilms Tumor Protein Isoform Ex4a(+), Wilms Tumor Protein Isoform Ex4a(+), Wilms Tumor Protein, Wilms Tumor Protein, Wilms Tumor Protein, Wilms Tumor Protein, EWS-WT1, EWS-WT1, EWS-WT1, EWS-WT1, NPHS4, NPHS4, NPHS4, NPHS4, WIT-2, WIT-2, WIT-2, WIT-2, WAGR, WAGR, WAGR, WAGR, AWT1, AWT1, AWT1, AWT1, GUD, GUD, GUD, GUD, Wilms Tumor Protein 1, Wilms Tumor Protein 1, Wilms Tumor Protein 1, Wilms Tumor Protein 1 |
Gene, Accession # | WT1, Gene ID: 7490, UniProt: P19544 |
Catalog # | abx001111 |
Price | please inquire |
Order / More Info | Wilms Tumor 1 (WT1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950