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Antigenic Specificity | Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 266-294 amino acids from the C-terminal region of human HNRNPA1. |
Other Names | ALS19, ALS20, HNRPA1, IBMPFD3, HNRPA1L3, hnRNP A1, hnRNP-A1, HNRNPA1, Heterogeneous nuclear ribonucleoprotein A1, Helix-destabilizing protein, Single-strand RNA-binding protein, hnRNP core protein A1, MGC102835, ALS19, ALS19, ALS19 , ALS19 , ALS20, ALS20, ALS20 , ALS20 , HNRPA1, HNRPA1, HNRPA1 , HNRPA1 , IBMPFD3, IBMPFD3, IBMPFD3 , IBMPFD3 , HNRPA1L3, HNRPA1L3, HNRPA1L3 , HNRPA1L3 , hnRNP A1, hnRNP A1, hnRNP A1 , hnRNP A1 , hnRNP-A1, hnRNP-A1, hnRNP-A1 , hnRNP-A1 , HNRNPA1, HNRNPA1, HNRNPA1 , HNRNPA1 , Heterogeneous nuclear ribonucleoprotein A1, Heterogeneous nuclear ribonucleoprotein A1, Heterogeneous nuclear ribonucleoprotein A1 , Heterogeneous nuclear ribonucleoprotein A1 , Helix-destabilizing protein, Helix-destabilizing protein, Helix-destabilizing protein , Helix-destabilizing protein , Single-strand RNA-binding protein, Single-strand RNA-binding protein, Single-strand RNA-binding protein , Single-strand RNA-binding protein , hnRNP core protein A1, hnRNP core protein |
Gene, Accession # | UniProt: P09651 |
Catalog # | abx029205 |
Price | please inquire |
Order / More Info | Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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