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Antigenic Specificity | Neuregulin 2 (NRG2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. |
Immunogen | KLH-conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2. |
Other Names | NRG2, NTAK, Pro-neuregulin-2, membrane-bound isoform, Neuregulin-2, Divergent of neuregulin-1, Neural and thymus-derived activator for ERBB kinases, Pro-NRG2, NRG-2, DON-1, Neural- and thymus-derived activator for ERBB kinases, NRG2, NRG2, NRG2 , NRG2 , NTAK, NTAK, NTAK , NTAK , Pro-neuregulin-2, Pro-neuregulin-2, Pro-neuregulin-2 , Pro-neuregulin-2 , membrane-bound isoform, membrane-bound isoform, membrane-bound isoform , membrane-bound isoform , Neuregulin-2, Neuregulin-2, Neuregulin-2 , Neuregulin-2 , Divergent of neuregulin-1, Divergent of neuregulin-1, Divergent of neuregulin-1 , Divergent of neuregulin-1 , Neural and thymus-derived activator for ERBB kinases, Neural and thymus-derived activator for ERBB kinases, Neural and thymus-derived activator for ERBB kinases , Neural and thymus-derived activator for ERBB kinases , Pro-NRG2, Pro-NRG2, Pro-NRG2 , Pro-NRG2 , NRG-2, NRG-2, NRG-2 , NRG-2 , DON-1, DON-1, DON-1 , DON-1 , Neural- and thymus-derived activator for ERBB kina |
Gene, Accession # | NRG2, NCBI: NP_001171864.1, NP_004874.1, NP_053584.1, NP_053585.1, NP_053586.1, UniProt: O14511 |
Catalog # | abx032739 |
Price | please inquire |
Order / More Info | Neuregulin 2 (NRG2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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