Edit |   |
---|---|
Antigenic Specificity | Nck-Interacting Kinase (NIK) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. HGK, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta. |
Immunogen | KLH-conjugated synthetic peptide between 618-649 amino acids from the C-terminal region of human NIK. |
Other Names | MAP3K14, NIK, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, MAP4K4, HGK, KIAA0687, Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, Nck-interacting kinase, MAP3K14, MAP3K14, MAP3K14 , MAP3K14 , NIK, NIK, NIK , NIK , Mitogen-activated protein kinase kinase kinase 14, Mitogen-activated protein kinase kinase kinase 14, Mitogen-activated protein kinase kinase kinase 14 , Mitogen-activated protein kinase kinase kinase 14 , NF-kappa-beta-inducing kinase, NF-kappa-beta-inducing kinase, NF-kappa-beta-inducing kinase , NF-kappa-beta-inducing kinase , Serine/threonine-protein kinase NIK, Serine/threonine-protein kinase NIK, Serine/threonine-protein kinase NIK , Serine/threonine-protein kinase NIK , MAP4K4, MAP4K4, MAP4K4 , MAP4K4 , HGK, HGK, HGK , HGK , KIAA0687, KIAA0687, KIAA0687 , KIAA0687 , Mitogen-activated protein kinase kinase kinase kinase 4, |
Gene, Accession # | NCBI: NP_001229488.1, NP_004825.3, NP_663720.1, UniProt: O95819 |
Catalog # | abx033810 |
Price | please inquire |
Order / More Info | Nck-Interacting Kinase (NIK) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950