Metabotropic Glutamate Receptor 8 (GRM8) Antibody from ABBEXA LTD

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Antigenic SpecificityMetabotropic Glutamate Receptor 8 (GRM8)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IHC
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DescriptionGRM8 antibody is a Rabbit polyclonal antibody against GRM8. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
ImmunogenA synthetic peptide of human GRM8.
Other NamesGLUR8, mGlu8, GPRC1H, MGLUR8, GRM8, Metabotropic glutamate receptor 8, GLUR8, GLUR8, GLUR8 , GLUR8 , mGlu8, mGlu8, mGlu8 , mGlu8 , GPRC1H, GPRC1H, GPRC1H , GPRC1H , MGLUR8, MGLUR8, MGLUR8 , MGLUR8 , GRM8, GRM8, GRM8 , GRM8 , Metabotropic glutamate receptor 8, Metabotropic glutamate receptor 8, Metabotropic glutamate receptor 8 , Metabotropic glutamate receptor 8
Gene, Accession #GRM8, Gene ID: 2918, UniProt: O00222
Catalog #abx002157
Priceplease inquire
Order / More InfoMetabotropic Glutamate Receptor 8 (GRM8) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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