Edit |   |
---|---|
Antigenic Specificity | Suppressor of Cytokine Signaling 1 (SOCS-1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Suppressor of Cytokine Signaling 1 (SOCS-1) antibody is a Rabbit polyclonal antibody for the detection of SOCS1. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |
Immunogen | Suppressor of cytokine signaling 1 |
Other Names | SOCS1, Suppressor Of Cytokine Signaling 1, STAT-Induced STAT Inhibitor 1, Tec-Interacting Protein 3, SOCS-1, SSI-1, TIP-3, SSI1, TIP3, SOCS1, SOCS1, SOCS1 , SOCS1 , Suppressor Of Cytokine Signaling 1, Suppressor Of Cytokine Signaling 1, Suppressor Of Cytokine Signaling 1 , Suppressor Of Cytokine Signaling 1 , STAT-Induced STAT Inhibitor 1, STAT-Induced STAT Inhibitor 1, STAT-Induced STAT Inhibitor 1 , STAT-Induced STAT Inhibitor 1 , Tec-Interacting Protein 3, Tec-Interacting Protein 3, Tec-Interacting Protein 3 , Tec-Interacting Protein 3 , SOCS-1, SOCS-1, SOCS-1 , SOCS-1 , SSI-1, SSI-1, SSI-1 , SSI-1 , TIP-3, TIP-3, TIP-3 , TIP-3 , SSI1, SSI1, SSI1 , SSI1 , TIP3, TIP3, TIP3 , TIP3 |
Gene, Accession # | SOCS1, Gene ID: 8651, UniProt: O15524 |
Catalog # | abx218825 |
Price | please inquire |
Order / More Info | Suppressor of Cytokine Signaling 1 (SOCS-1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950