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Antigenic Specificity | Tyrosine-Protein Kinase Fgr (FGR) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta 2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunogen | Purified recombinant fragment of human FGR expressed in E. Coli. |
Other Names | C-FGR, FGR protein, P55-FGR, Proto-oncogene tyrosine-protein kinase FGR, SRC2, kinase Fgr, FGR, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Oncogene FGR, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene, FLJ43153, MGC75096, c-src2, p55c-fgr, p58c-fgr, OTTHUMP00000003603, c-fgr protooncogene, c-src-2 proto-on, p58-Fgr, Tyrosine-protein kinase Fgr, Proto-oncogene c-Fgr, C-FGR, C-FGR, C-FGR , C-FGR , FGR protein, FGR protein, FGR protein , FGR protein , P55-FGR, P55-FGR, P55-FGR , P55-FGR , Proto-oncogene tyrosine-protein kinase FGR, Proto-oncogene tyrosine-protein kinase FGR, Proto-oncogene tyrosine-protein kinase FGR , Proto-oncogene tyrosine-protein kinase FGR , SRC2, SRC2, SRC2 , SRC2 , kinase Fgr, kinase Fgr, kinase Fgr , kinase Fgr , FGR, FGR, FGR , FGR , Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog , Gardner-R |
Gene, Accession # | Gene ID: 2268, UniProt: P09769 |
Catalog # | abx010780 |
Price | please inquire |
Order / More Info | Tyrosine-Protein Kinase Fgr (FGR) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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