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Antigenic Specificity | Serine/threonine-Protein Kinase VRK1 (VRK1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. |
Immunogen | KLH-conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1. |
Other Names | VRK1, 51PK, PCH1A, Vaccinia related kinase 1, Vaccinia-related kinase 1, PCH1, Serine/threonine-protein kinase VRK1, VRK1, VRK1, VRK1 , VRK1 , 51PK, 51PK, 51PK , 51PK , PCH1A, PCH1A, PCH1A , PCH1A , Vaccinia related kinase 1, Vaccinia related kinase 1, Vaccinia related kinase 1 , Vaccinia related kinase 1 , Vaccinia-related kinase 1, Vaccinia-related kinase 1, Vaccinia-related kinase 1 , Vaccinia-related kinase 1 , PCH1, PCH1, PCH1 , PCH1 , Serine/threonine-protein kinase VRK1, Serine/threonine-protein kinase VRK1, Serine/threonine-protein kinase VRK1 , Serine/threonine-protein kinase VRK1 |
Gene, Accession # | UniProt: Q99986 |
Catalog # | abx033380 |
Price | please inquire |
Order / More Info | Serine/threonine-Protein Kinase VRK1 (VRK1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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